Addiction Medicine in Serious Illness: Introduction
This series within the Medicine Minds Library will explore the challenges of managing Substance Use Disorder (SUD) in hospice and serious illness care. It will emphasize the complexities of MOUD medications and will present clinical cases highlighting complex medication management and psychosocial factors encountered in practice. Additionally, it underscores SimsRx’s commitment to supporting clinicians through education and expert guidance on addiction medicine in Serious Illness.
10/16/20251 min read
At SimsRx, we recognize that addiction medicine is becoming increasingly relevant in the context of serious illness and hospice care, especially as clinicians face more complex pain management challenges involving Substance Use Disorder (SUD). To support healthcare providers in navigating these complexities, we are proud to introduce a new Addiction Medicine Series within our Medicine Minds library. This series aims to deepen understanding of managing Opioid Use Disorder (OUD) in patients with serious illness, emphasizing safe medication practices, risk management, and informed clinical decision-making.
Managing MOUD in the setting of serious illness requires balancing effective symptom control with the unique pharmacologic and psychosocial considerations of each patient. The series will explore critical topics such as medication induction, dose titration, and the safety of switching or rotating medications like buprenorphine and methadone—highlighting strategies to minimize risks such as overdose or adverse interactions. Additionally, we will examine approaches for addressing complex psychosocial factors, polysubstance use, and the challenges of coordinating care across multiple disciplines.
Our motivation stems from the increasing demand for guidance on how to safely incorporate addiction treatment into serious illness care. We are committed to equipping clinicians with the knowledge and skills necessary to navigate these nuanced situations confidently. Through ongoing education, case discussions, and expert insights, we aim to foster safer, more effective practices that improve patient safety and outcomes.
In the coming months, we will weave addiction medicine topics into our blog, covering critical issues such as medication induction, pain management strategies, and managing complex substance use scenarios—all tailored to the needs of patients facing serious illnesses.
We invite you to follow our Medicine Minds Blog as we explore these vital topics, to bridge the gap between addiction medicine and serious illness care. We aim to foster safer, more effective clinical practices by sharing knowledge, supporting clinicians with expert guidance, and promoting a nuanced understanding of addiction medicine in complex patient populations.


